Rejuran 10 Solutions to Look 10 Years Younger

Rejuran skin booster

woman touch her face.Banner for Rejuran treatment


REJURAN is a “New Concept Healer” made of polynucleotides(PN), which are DNA fragments of specific size derived from wild salmon. Makes your skin young and healthy naturally by delivering the highly bio-compatible polynucleotides directly into the skin.


Excellent Recovering Effect

REJURAN activates the self-regerative ability of the skin and improves the appearance of various skin concerns such as wrinkles, scars, large pores, redness and pigmentation, etc.

Improvement of Skin Elasticity and Fine Wrinkles

REJURAN promotes the secretion of collage and restores Extra Cellular Matrix to recover thin and damaged skin inside caused by aging, while simultaneously improving skin elasticity and reducing the appearance of wrinkles.

Improvement of Skin Tone and Texture

REJURAN improves pigmentation and overall brightness of the complexion which is helpful in recovering the tonicity and luminosity of smoother skin texture.

Proven Safety

REJURAN is composed of high biocompatible DNA fragment with no adverse reaction.

Natural Skin Beauty Effects

REJURAN gives you the natural skin beauty effects resulting from increasing skin elasticity and hydration from deep inside of the skin.


Rejuran is a medical device made from purified polynucleotides (PN).

PN (Polynucleotide)

DNA fragments extracted from wild salmon managed by the company’s patent technology, DOTTM

Clear, colorless viscous solution

Slowly degrading while maintaining uniform structure in tissue

Proven to be the most compatible to human skin without causing any adverse effects

Stimulating skin’s own reparative and restorative capabilities

Skin elasticity improvement by recovering the biological condition of the dermis and epidermis

Not Too Much, Not Too Little

REJURAN is the safest aesthetic procedure that functions by improving the skin’s own regenerating capabilities


•REJURAN® is manufactured in world class production facilities, certified with KGMP (Korea Good Manufacturing Practice), ISO13485 and etc.

•REJURAN® is terminally moist-heat sterilized product. ®

•REJURAN has own patent technology of extraction, purification and distillation for the active ingredient, PN [Patent No. 10-1476381].


Rejuran offers 4 different products to meet your specific needs

Let Nature Nourish Your Beauty


REJURAN Healer, I , S

Skin Healer for Full Face, Eye Wrinkles and Sunken Scars!



Powerful Synergistic Effect in Rejuvenation and Hydration!

High biocompatible DNA fragment extracted from wild salmon that activates self-regeneration ability of the skin

A natural substance that helps keep the skin moisturized and hydrated

Pre-incorporated lidocaine that reduces treatment-related pain and enhances patient comfort

rejuran-hb product

Enhanced REJURAN

with Improved Comfort and Faster Results!


Double Effect in Rejuvenation(PN) and Hydration(HA)

REJURAN® HB gives both the skin healing strengths of PN and the deep skin hydrating benefits of HA

Improved Patient Comfort

REJURAN® HB contains lidocaine to enhance treatment comfort and optimize the injection experience

What are the Benefits of REJURAN ?

REJURAN is a very potent and advanced skin rejuvenation treatment that it can help turn back the clock with its cellular repair properties and help you achieve youthful, natural healthy skin.


10 Solutions to Look 10 Years Younger

A Fundamental Change in the Skin with REJURAN®


What Can You Expect After the Treatment?

Clinical Studies

REJURAN promotes cell growth through fibroblast proliferation resulting in more collagen production


Ref ) Chang sik Pak et al., A phase 3, randomized, double-blind, matched-pairs, active-controlled clinical trial and preclinical animal study to compare the durability, efficacy and safety between polynucleotide filler and hyaluronic acid filler in the correction of crow’s feet; JKMS 2014;201-209

REJURAN restores skin elasticity with regenerating epidermis and dermis healthy from thinned and damaged skin

Ref ) Chang sik Pak et al., A phase 3, randomized, double-blind, matched-pairs, active-controlled clinical trial and preclinical animal study to compare the durability, efficacy and safety between polynucleotide filler and hyaluronic acid filler in the correction of crow’s feet; JKMS 2014;201-209

REJURAN treatment results in increased epidermal and dermal skin thickness forming a strong defense barrier against environmental and non-environmental factors that cause premature skin aging


Ref ) Seoul national university bundang hospital report

REJURAN increases skin hydration by 14.69% and skine lasticity by 21.78%


Ref ) Long chain polynucleotides gel and skin biovitalization. Journal of Plastic Dermatology 2007; 3, 3

Clinical Study - REJURAN Healer

Full Face Rejuvenation

A total of 4 REJURAN treatments in two-week intervals

The pore and skin thickness were markedly improved in 30s, whereas skin tone, melanin, wrinkles, and sagging were noticeably improved in 40s


Ref ) Park, K. Y., Seok, J., Rho, N. K., Kim, B. J., & Kim, M. N. (2015). Long-chain polynucleotide filler for skin rejuvenation: efficacy and complications in five patients. Dermatologic Therapy, 29(1), 37–40.


Clinical Study - REJURAN i

Under-Eye Area Rejuvenation

REJURAN i treatments were performed every two weeks for a total of three times, over a total of 12 weeks

PN administration reduces or even completely eliminates crow’s feet and fine wrinkles around eyes, and also improves elasticity around eyes area

Individual results may vary.
Individual results may vary.

Ref ) A Phase III, Randomized, Double-Blind, Matched-Pairs, Active-Controlled Clinical Trial to Compare the Durability, Efficacy and Safety between Polynucleotide Filler and Hyaluronic Acid Filler in the Correction of Crow’s Feet, In house report, 2014

Clinical Study - REJURAN s

Scar Treatment

The experimental group and control group were randomly assigned to compare the efficacy for 16 weeks
– Experimental group: fractional laser + REJURAN®s
– Control group: fractional laser + saline

The Vancouver Scar Scale (VSS), global photographic assessment, and objective scar were assessed using 3D camera at baseline and after surgery

Adjuvant administration of PN along with conventional fractional laser treatment led to more favorable effect in would healing and post-operative scar prevention after thyroidectomy


Ref ) Preventive Effect of Polynucleotide on Post-thyroidectomy Scars: A Randomized, Double-Blinded, Controlled Trial Lasers inSurgery and Medicine (SCI), 2018, 755-762

3D Image Antera

Individual results may vary.


REJURAN® is not like conventional filler or laser treatments.
It works by activating the skin’s own regenerative ability to restore own collagen structure and increase skin elasticity.

This allows your skin to recover with a course of 4 treatments with intervals of 2-3 weeks between sessions, followed by a treatment every six months to nurture a healthy skin condition.

While there may be some initial slight swelling or papules on the treated areas immediately after the treatment, this will subside within 24 hours and you can go about your day activities as usual.

For the best results, the treatment should cover your entire face rather than just the eyes area, REJURAN® improves aging and damaged skin.

Composed of highly bio-compatible DNA fragments, REJURAN® fundamentally restores the skin without any adverse effects. It is also completely safe and effective for those areas that are difficult to treat with hyaluronic acid filler or toxin.

– Not when receiving treatment with REJURAN®. Utilizing the main ingredient PN, it has a dose-dependent effect that will make your skin fully saturate and derive optimal benefits.

– Inject with 27- or 30-gauge needle just beneath the dermis after mixing with the lidocaine.

– Anti-pain medications can be taken before the treatment.

– Forehead, Glabella, Around Eyes: Needle – Midface, Jawline: Cannula
– Around lips: Needle

– This depends on the type of dermal filler or injectable used.
       It can be done in combination with dermal filler that the immune-related reactions have rarely reported.
       When combined, make sure to target different layer of the skins.

– Theoretically, it is safer to perform REJURAN® treatment weeks before other dermal filler or injectable treatment.

– Patient evaluation is needed before the treatment for those who had other facial injectable in previous. REJURAN® is recommended after 3-6 months follow-up of the previous treatment.

icon email